INCUBATOR GRANT PROJECT

Preventing the transmission of mutant mitochondrial DNA

Incubator Grants

$25,000 AUD

01/04/2014 → 31/01/2016

Carolyn Sue

Researcher

Professor Justin St John

Research Institution

Monash Institute of Medical Research-Prince Henry’s Institute

Project Name

Preventing the transmission of mutant mitochondrial DNA

Project Details

Professor St John’s previous research has produced groundbreaking results in the field of mitochondrial DNA and development. He has extensively studied how mitochondrial DNA interacts with the chromosomal genome in eggs, embryos and later during development. The work he is undertaking with the Mito Foundation will determine if replacing the mitochondrial genome is a safe and healthy practice for patients carrying mitochondrial DNA mutations. If it is, it will provide a reproductive technology to help prevent future generations from inheriting mitochondrial DNA mutations, which can have severe affects on health and quality of life.