01/04/2014 → 31/01/2016
Professor Justin St John
Monash Institute of Medical Research-Prince Henry’s Institute
Preventing the transmission of mutant mitochondrial DNA
Professor St John’s previous research has produced groundbreaking results in the field of mitochondrial DNA and development. He has extensively studied how mitochondrial DNA interacts with the chromosomal genome in eggs, embryos and later during development. The work he is undertaking with the Mito Foundation will determine if replacing the mitochondrial genome is a safe and healthy practice for patients carrying mitochondrial DNA mutations. If it is, it will provide a reproductive technology to help prevent future generations from inheriting mitochondrial DNA mutations, which can have severe affects on health and quality of life.