Building a National Clinical Database

$75,000 AUD

01/06/2018 → 30/06/2019

The lack of knowledge about mitochondrial disease (mito) means that it is extremely difficult to assess the effectiveness of treatments…

Beyond the Exome

$75,000 AUD

16/04/2018 → 15/04/2019

New genomic technologies are transforming diagnosis of mitochondrial disease (mito) and other inherited diseases but perhaps half of all children…

Functionalism of mitochondrial Complex I accessory subunits

$12,250 AUD

23/01/2017 → 28/02/2019

Marris Dibley is exploring what can go wrong inside the tiny machinery of the mitochondria. Marris is a PhD candidate…

Functionalisation of mitochondrial Complex I accessory subunits in health and disease

$12,250 AUD

28/02/2016 → 28/02/2019

Mitochondrial complex I is the largest of the five enzymes which combine to perform oxidative phosphorylation, the primary source of…

Impaired gene expression causes mitochondrial disease

$10,500 AUD

01/08/2014 → 01/02/2018

Did you know that our cells actually switch genes on and off at certain times, depending on input from their…

Neuropathogenic mechanisms of mitochondrial dysfunction

$45,000 AUD

01/07/2014 → 23/07/2017

Existing treatments for mitochondrial disease (mito) only alleviate symptoms rather than addressing their underlying cause. Scientists like Sophia Frentz are working…

Global Metabolic Profiling of Mitochondrial Diseases

$22,000 AUD

01/12/2015 → 01/12/2016

Dr Anthony Dona works in the field of metabolic profiling at the University of Sydney’s Kolling Institute of Medical Research.…

Drug Screening to Rescue OXPHOS Defective Cells

$25,000 AUD

01/11/2015 → 01/12/2016

Professor Mike Ryan is leading a project to discover compounds that can treat mitochondrial disease (mito).  He is the head…

Determining the genetic basis of Leigh Syndrome

$5,347 AUD

01/10/2013 → 01/10/2016

The most common childhood mitochondrial disease presentation is Leigh syndrome, which is a progressive neurodegenerative disease with an onset that…

Identification of novel pathogenic mutations in genes causing inborn errors of metabolism

$9,357 AUD

27/08/2014 → 01/08/2016

There are over 1,500 genes involved in the normal functioning of the mitochondria. So far, only about 250 genes have…