The Mito Foundation's purpose is to end suffering from mitochondrial disease (mito). To reach that goal, we are working towards preventions, treatments, and cures for mito. We are also working to make these easily accessible to people with mito.

Our Research and Medical Grant Program drives research into mito. We do this by identifying and funding impactful research and clinical work. Today, Mito Foundation is the second largest philanthropic funder of mito research worldwide. We have funded over 100 research grants.

Since 2010, we have supported researchers to make significant progress in mito research. Together, we are already improving the lives of people impacted by mito. Help us continue this important work by donating today.

We've contributed

$8 million

to mito research worldwide.

Research highlights from 2023

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Across 6 projects, every $1 we invested led to a further $5.30 in additional funding

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6 research studies were made available to the Australian mito community 

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Identified a new mito gene, CRLS1

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Pre-clinical testing of a gene editing technology to treat mito

Research priority areas

We're committed to achieving the greatest impact for the mito community. To do this, we aim to fund the world's best mito research across 4 priority areas.

Seed Icon Understanding mito

Understanding the molecular and cellular processes involved in mito is essential. This is the foundation for much of mito research.

Since 2010, Mito Foundation has funded over 40 grants in this area of research. Discoveries from these projects are leading to advancements in:

  • diagnosis
  • prevention, treatments and cures.

Our funding has led to significant progress in understanding ultra-rare forms of mitochondrial diseases like Sengers Syndrome, Mohr-Tranbjaerg Syndrome, MEGCANN, and ATAD3-related mito. These studies offer hope for future treatments.

We funded the development of 2 new mouse models targeting forms of mito caused by the genes PTCD1 and TACO1. Our support has also advanced stem cell models for LHON and POLG-related mito. This research informs the development of effective treatments and therapies.

Budding Plant Icon Improving diagnosis
Watering Can Icon Improving health care
Plant Icon Advancing prevention, treatments, and cures

"Early diagnosis has saved him from numerous related health conditions and possible death at an early age."

— Clare Hamman, Julian’s mum

Read Julian's story.

Researcher journey

We regularly support researchers, and their teams, over many years, through multiple grants. This develops expertise and a stronger mito workforce. It also enables researchers to build on their discoveries. Over time, these research journeys have a great impact on the field of mito research and the mito community.

Associate Professor David Stroud's work pioneering a new diagnostic technique

Quantitative proteomics is a tool that has the potential to drastically improve mito diagnostic rates from around 50% toward 70%. Proteomics can be used to diagnose people who are still living without a diagnosis after traditional methods failed to provide an answer.

Learn more

We've funded over

100

research grants

Contribute towards a brighter future for the mito community. Join the Mito Registry to be contacted about relevant clinical studies.

We offer a range of funding opportunities for research focussed on primary mitochondrial disease.