Research for better outcomes

Improving our understanding of the complex biological mechanisms involved in mito is key to advancing diagnostics and prevention, developing effective treatments and ultimately, cures for mito. Mito Foundation is committed to supporting research that increases knowledge of the genetics of mito, and the cellular and molecular mechanisms involved in the pathogenesis and progression of mito.

Patients often spend years on the ‘diagnostic odyssey’, searching for answers; many remain undiagnosed or misdiagnosed.

Mito Foundation is committed to improving the speed and accuracy of diagnosis of mito through genetic testing and other pioneering techniques. A timely diagnosis enables patients earlier access to specialised care and management, support services, family planning and reproductive options, and provides greater opportunity for patients to access emerging therapies through participation in clinical trials.

The Mito Foundation is committed to advancing research that improves current treatments, care and best practice management. This includes research initiatives that help:

• inform and implement improved standards of care
• enhance equitable and timely access to mito-specific healthcare services and medical professionals
• improve patient and family support practices, including those that improve quality of life, psychosocial impacts and palliative care.

Current therapies for mito are very limited, primarily revolving around supportive, symptomatic treatment only.  Mito Foundation is committed to investing in the best research to advance the discovery and development of potential new treatments, including gene-based therapies such as gene replacement and gene editing.

In addition, advancement in preventative strategies including mitochondrial donation, which may reduce the incidence of mito and improve reproductive confidence in families, is a Mito Foundation funding priority.